Services
Our services are based on the Translational Pharmacology Approach (TPA) with the aim of improving the predictive value of the experimental models used to qualify the efficacy and safety of a drug candidate.
We propose a large choice of experimental platforms:
- Human Tissues from Healthy donors and Patients. Tissues can be fresh, frozen at -80°C or paraffin embedded (FFPE)
- Human primary cells in Air-Liquid Interface (ALI) cultures
- Human and animal isolated tissues freshly isolated for studies of myogenic and neurogenic contractions/relaxations
- Experimental models in vivo on mice and rats, mimicking the pathology of interest
Fields of Expertise
Translational Pharmacology
The challenge for Translational Pharmacology is to improve the predictive value of the tools that are used to qualify the efficacy and safety of a drug candidate.
Our goal is to improve the predictivity of preclinical studies by using different experimental platforms:
- in vitro: Human primary cells in Air-Liquid Interface (ALI) cultures
- ex vivo: Human and animal isolated tissues freshly isolated for studies on myogenic and neurogenic contractions/relaxations
- in vivo models using mice and rats, mimicking the pathology of interest
Nutraceuticals and Plant Extracts
Nutraceuticals
The term “nutraceutical” combines the two words of “nutrient,” which is a nourishing food component, and “pharmaceutical,” which is a medical drug. The name was coined in 1989 by Stephen DeFelice, founder and chairman of the Foundation for Innovation in Medicine, USA.
Humana Biosciences offers experimental models to evaluate the absorption of Nutraceuticals by the gastro-intestinal tract, by using human cells and tissues, as well as animal tissues.
Our expertise allows us to deliver reliable results and to help our clients reduce the time to market for their newly developed Nutraceuticals.
Plant extracts
Plant extract refers to a product that is formed through an extraction and separation process where plants are used as raw materials. Generally the original components of the plants are not changed. There are also a small amount of liquid or oily plant extract products.
Our clients benefit from our long experience in handling and evaluating plant extracts by using in vitro, ex vivo and in vivo experimental models. Our expertise allows us to deliver reliable results and to help our clients reduce the time to market for their newly developed plant extracts for a variety of applications (pharmaceuticals, nutraceuticals, cosmetics…)
Human Tissues from Healthy donors and Patients
Tissues can be fresh, frozen at -80°C or paraffin embedded (FFPE)
Human tissues are guaranteed to be obtained from consenting donors who did not receive any financial incentive.
We guarantee the respect of the Convention for the protection of human rights and dignity of human beings concerning applications of biology and medicine: “Convention on Human Rights and Biomedicine”.
Our sources are compliant with the highest international ethical guidelines.
Our Company is titular of several authorizations for preparation, manipulation, import/export of human tissues, delivered by the French Ministry of Research.
Consulting
Save both time and money: our 35 years’ expertise is available when you need it:
- Identification of the best Experimental Models
- Study Plan optimization
- Evaluation of Therapeutic Switching opportunities
- Designing new drug formulations
