About Stefano Palea

This author Stefano Palea has created 4 entries.

A mouse preclinical model of Benign Prostatic Hyperplasia (BPH) useful to test drug candidates

Combined Sabal and Urtica Extracts (WS® 1541) Exert Anti-proliferative and Anti-inflammatory Effects in a Mouse Model of Benign Prostate Hyperplasia Prostagutt Forte (WS® 1541) was tested using an innovative experimental model of BPH in transgenic mice where Prolactin is overexpressed in luminal prostatic cells. We are pleased to announce the online publication on Frontiers in Pharmacology of a paper in collaboration with Dr. Vincent Goffin (Inserm, Unit 1151, Paris, France) and the Company Dr. Willmar Schwabe GmbH &Co. (Germany). This experimental model is unique since,

Partnership with S.A.F.AN. Bioinformatics


S.A.F.AN. Bioinformatics is a private company specializing in fee-for-service chemo-informatic and structural bioinformatics studies based in Italy. This company has developed a proprietary in silico profiling technology for small molecules, ranking the binding of one compound to 3200 protein targets belonging to 14 different classes. S.A.F.AN. Bioinformatics is specialized in chemoinformatic and structural bioinformatics research. Therefore, the company aims to reposition drugs by using a specific computational method in order to hasten the repurposing process at a reduced cost. Recently, they launched SAFAN-ISP,

Partnership with Sicoval

Created in 2002, Prologue Biotech is a business incubator, managed by the Sicoval, dedicated to biotechnology/health companies.  It supports their launch and development providing a dedicated tool answering specific needs of infrastructure. The Sicoval aims to support young biotech companies providing tools to succeed, laboratories, appropriate facilities, shared resources and economic promotion. Prologue Biotech proposes animal facilities services, answering to Biotechs involved in preclinical assays and expertise. Prologue Biotech is certified ISO 9001-2008, which ensure the quality and willingness to constantly improve the provided services and their consistency with

Partnership with CREFRE

crefre partner

The CREFRE, Regional Center of Functional Exploration and Experimental Resources, (based in Toulouse, France) is a mixed unit Inserm/Paul Sabatier University endowed with highly sophisticated equipment, included animal breeding. CREFRE is specialized in the production of Genetically Modified Animals, the pathophysiological exploration of transgenic animal models (mice, rats and zebrafish) and the phenotyping. The laboratory, based in the IUCT Oncopole, has centralized services for transgenesis, cryopreservation and decontamination, but also non-invasive exploration, and experimental animal breeding. The Regional Center